PGD in Italy: 1PB Testing

- PGD on polar bodies
- Preconception genetic diagnosis
- Technical description of the procedure
- Mutation analysis
- Limitations
- Advantages
- Ethical issues



Next : PGD on polar bodies

 

• What is PGD
   
• Indications for PGD
  - Recurrent Miscarriage
  - Unsuccessful IVF Cycles (>2)
  - Unexplained Infertility
  - Advanced Maternal Age
  - Male Factor Infertility
  - History of Chromosomally Abnormal Child or Pregnancy
  - Family history of structural chromosomal condition
  - Family history of X-linked disease
  - Inherited genetic disorders
  

• How PGD is performed
  - Oocyte aspiration
  - Fertilization and Embryo Culture
  - Polar body removal and/or blastomere biopsy
  - Preimplantation Genetic - Diagnosis in blastomeres
  - Embryo transfer and implantation
   

• Genetic diseases that can be diagnosed by PGD
   

• PGD in Italy: 1PB Testing
  - PGD on polar bodies
  - Preconception genetic diagnosis
  - Technical description of the procedure
  - Mutation analysis
  - Limitations
  - Advantages
  - Ethical issues