PGD of aneuploidy
GENOMA tests chromosomes X, Y, 13, 15, 16, 17, 18, 21 and
22. This is based on trisomies arriving to term
(XY,13,18,21), common in spontaneous abortions (16,22,15,21)
and most common aneuploidies found in day 3 embryos
(22,16,21,15,17). Aneuploidy screening can be also performed
in combination with PGD for single gene disorders (by using
PCR) and/or HLA matching, PGD for cancer predisposition and
PGD for late on-set disorders, as well as in combination
with PGD for translocation.
In addition, for those cells with questionable results, we
reanalyze with telomeric probes, which bind to a different
locus, and therefore may discriminate probe overlaps or
split signals, thus reducing our error rate to very low
Laboratory time is 6-12 hours after sample arrival; perhaps
longer if a third round of telomeric probes is needed.
We can accommodate requests for additional analysis of other
chromosomes not involved in the standard test. For preparing
and scheduling a PGD case please follow our "PGD for
aneuploidy information booklet". For more info on PGD for
Aneuploidy Screening please click here.
PGD of Translocations