Indications for PGD

Male Factor Infertility

Approximately one-half of all infertility is caused by sperm abnormalities. Many sperm disorders are due to a chromosome abnormality such as aneuploidy or a structural chromosome abnormality.

Men carrying a balanced translocation chromosome are at risk of producing sperm with a structural chromosome abnormality.

Several studies have determined that approximately 3-8% of sperm from normal, fertile men are aneuploid and 27-74% of sperm from men with severe infertility are aneuploid.

Couples with infertility due to male factor, should consider chromosome analysis on the males sperm prior to IVF.

Next : History of Chromosomally Abnormal Child or Pregnancy


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Preimplantation Genetic Diagnosis

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