Indications for PGD
Male Factor Infertility
one-half of all infertility is caused by sperm
abnormalities. Many sperm disorders are due to a chromosome
abnormality such as aneuploidy or a structural chromosome
Men carrying a balanced translocation chromosome are at
risk of producing sperm with a structural chromosome
Several studies have determined that
approximately 3-8% of sperm from normal, fertile men are
aneuploid and 27-74% of sperm from men with severe
infertility are aneuploid.
Couples with infertility due to male factor, should consider
chromosome analysis on the males sperm prior to IVF.
History of Chromosomally Abnormal Child or Pregnancy