Accuracy of PGD for HLA matching
The techniques used in PGD for HLA matching compares the
mother?s DNA and father?s DNA to that of the affected child.
It is imperative that both parents are the biologic/genetic
parents of the affected child to ensure that it is possible
to find HLA-matched embryos. If non-paternity or
non-maternity is discovered, pursuit of an HLA-matched
embryo will not be successful.
Overall, PGD is an accurate process for determining whether
the HLA type of an embryo matches that of an affected child.
So far we no misdiagnosis for HLA typing has been reported,
we estimate the risk to be lower than 1%.
PGD for inherited predisposition to cancer